RYTM

RHYTHM PHARMACEUTICALS, INC.CIK 1649904 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

—

0 trades · 0 insiders

Open-mkt sales · 90d

$57.59M

40 trades · 6 insiders

Net · 90d

$-57.59M

Insiders on file

AI insights for RYTM PRO

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AI insights for RYTM

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date

Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Meeker David P	President and CEO, Director	52	$626.7K	$15.91M	2026-09-14
Smith Hunter C	Chief Financial Officer	148	$0	$26.04M	2026-08-31
Joshi Manher	Chief Medical Officer	4	$0	$0	2026-08-17
Garfield Alastair	Chief Scientific Officer	24	$0	$1.91M	2026-08-13
Shulman Joseph	Chief Technical Officer	126	$0	$16.36M	2026-08-13
Lee Jennifer Kayden	EVP, Head of North America	108	$0	$25.84M	2026-08-13
Mazabraud Yann	EVP, Head of International	75	$0	$19.50M	2026-08-12
TETRAULT LYNN A.	Director	37	$0	$5.40M	2026-06-24
Arbuckle Stuart A	Director	18	$0	$0	2026-06-24
JEAN CHRISTOPHE	Director	19	$0	$0	2026-06-24
GOOD JENNIFER L	Director	43	$0	$4.27M	2026-06-24
MCGIRR DAVID W J	Director	23	$0	$4.27M	2026-06-24
German Christopher Paul	Corporate Controller & CAO	45	$0	$1.59M	2026-05-15
Popovits Kimberly J	Director	2	$0	$0	2026-04-01
Mathers Edward T	Director	19	$0	$0	2026-03-12
Cramer Pamela J.	Chief Human Resources Officer	103	$0	$10.98M	2026-02-11
Bedrosian Camille L	Director	13	$0	$0	2025-06-24
Roberts William T.	Chief Accounting Officer	14	$0	$80.5K	2023-03-29
Manning Linda Shapiro	Chief Medical Officer	4	$0	$0	2022-02-09
Foley Todd	Director, 10% Owner	55	$1.70M	$50.56M	2021-03-15
Kelner Simon	Chief Human Resources Officer	6	$0	$0	2021-02-11
Stewart Murray	Chief Medical Officer	6	$0	$0	2021-02-11
RA CAPITAL MANAGEMENT, L.P.	Other	9	$0	$9.93M	2020-12-03
Desikan Nithya	Chief Commercial Officer	16	$0	$1.55M	2020-08-31
Shah Rajeev M.	10% Owner	3	$0	$3.47M	2020-06-29
Gottesdiener Keith Michael	CEO and President	29	$0	$2.48M	2020-03-09
Van der Ploeg Leonardus H.T.	Chief Scientific Officer	32	$0	$2.73M	2019-05-31
TRV GP, LLC	10% Owner	1	$0	$0	2018-08-30
Exter Neil	Director	4	$0	$0	2018-06-06
OrbiMed Capital GP V LLC	10% Owner	4	$0	$4.66M	2018-05-22
Fiedorek Fred T.	Chief Medical Officer	2	$0	$0	2018-02-14
PFIZER INC	10% Owner	5	$680.0K	$0	2017-10-10
Hadley Harbor Master Investors (Cayman) L.P.	10% Owner	2	$0	$0	2017-10-10
MPM BIOVENTURES V, L.P.	10% Owner	4	$1.70M	$0	2017-10-10
Viswanathan Ravi	10% Owner	5	$9.35M	$0	2017-10-10
NEA Partners 13, Limited Partnership	10% Owner	5	$9.35M	$0	2017-10-10
THIRD ROCK VENTURES LP	10% Owner	3	$0	$0	2017-10-10
Ipsen, S.A.	10% Owner	5	$340.0K	$0	2017-10-10
BASKETT FOREST	10% Owner	5	$9.35M	$0	2017-10-10
SANDELL SCOTT D	10% Owner	5	$9.35M	$0	2017-10-10
KERINS PATRICK J	10% Owner	5	$9.35M	$0	2017-10-10
MOTT DAVID M	10% Owner	5	$9.35M	$0	2017-10-10
BARRETT M JAMES	10% Owner	5	$9.35M	$0	2017-10-10
ISALY SAMUEL D	10% Owner	3	$6.04M	$0	2017-10-10
Deerfield Mgmt L.P.	10% Owner	6	$6.04M	$0	2017-10-10
BARRIS PETER J	10% Owner	5	$9.35M	$0	2017-10-10
BAKER JULIAN	Other	6	$15.04M	$0	2017-10-05

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Meeker David P	President and CEO	M Exercise deriv	2026-09-14	2026-09-14	50,000	—	$0	15,431	SEC↗
Meeker David P	President and CEO	M Exercise	2026-09-14	2026-09-14	50,000	$6.05	$302.5K	289,258	SEC↗
Meeker David P	President and CEO	S Sale	2026-09-14	2026-09-14	1,817	$104.55	$190.0K	241,558	SEC↗
Meeker David P	President and CEO	S Sale	2026-09-14	2026-09-14	8,698	$103.43	$899.6K	243,375	SEC↗
Meeker David P	President and CEO	S Sale	2026-09-14	2026-09-14	30,746	$102.35	$3.15M	252,073	SEC↗
Meeker David P	President and CEO	S Sale	2026-09-14	2026-09-14	6,439	$101.75	$655.2K	282,819	SEC↗
Meeker David P	President and CEO	S Sale	2026-09-14	2026-09-14	2,300	$105.19	$241.9K	239,258	SEC↗
Meeker David P	President and CEO, Director	M Exercise deriv	2026-09-14	2026-09-14	50,000	—	$0	15,431	SEC↗
Meeker David P	President and CEO, Director	S Sale	2026-09-14	2026-09-14	2,300	$105.19	$241.9K	239,258	SEC↗
Meeker David P	President and CEO, Director	S Sale	2026-09-14	2026-09-14	1,817	$104.55	$190.0K	241,558	SEC↗
Meeker David P	President and CEO, Director	S Sale	2026-09-14	2026-09-14	8,698	$103.43	$899.6K	243,375	SEC↗
Meeker David P	President and CEO, Director	S Sale	2026-09-14	2026-09-14	30,746	$102.35	$3.15M	252,073	SEC↗
Meeker David P	President and CEO, Director	S Sale	2026-09-14	2026-09-14	6,439	$101.75	$655.1K	282,819	SEC↗
Meeker David P	President and CEO, Director	M Exercise	2026-09-14	2026-09-14	50,000	$6.05	$302.5K	289,258	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2026-08-31	2026-09-01	57,187	—	$0	3,813	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-08-31	2026-09-01	28,188	$106.20	$2.99M	114,024	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2026-08-31	2026-09-01	57,187	$25.79	$1.47M	176,798	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-08-31	2026-09-01	23,072	$104.59	$2.41M	153,726	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-08-31	2026-09-01	11,514	$105.37	$1.21M	142,212	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2026-08-31	2026-09-01	57,187	—	$0	3,813	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-08-31	2026-09-01	28,188	$106.20	$2.99M	114,024	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-08-31	2026-09-01	11,514	$105.37	$1.21M	142,212	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-08-31	2026-09-01	23,072	$104.59	$2.41M	153,726	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2026-08-31	2026-09-01	57,187	$25.79	$1.47M	176,798	SEC↗
Joshi Manher	Chief Medical Officer	A Award deriv	2026-08-17	2026-08-18	50,000	—	$0	50,000	SEC↗
Joshi Manher	Chief Medical Officer	A Award deriv	2026-08-17	2026-08-18	25,000	—	$0	25,000	SEC↗
Joshi Manher	Chief Medical Officer	A Award deriv	2026-08-17	2026-08-18	25,000	—	$0	25,000	SEC↗
Joshi Manher	Chief Medical Officer	A Award deriv	2026-08-17	2026-08-18	50,000	—	$0	50,000	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise deriv	2026-08-13	2026-08-14	21,601	—	$0	0	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise deriv	2026-08-13	2026-08-14	35,000	—	$0	36,283	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2026-08-13	2026-08-17	2,024	—	$0	5,945	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise	2026-08-13	2026-08-14	21,601	$6.80	$146.9K	75,834	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise	2026-08-13	2026-08-14	35,000	$24.29	$850.1K	54,233	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	S Sale	2026-08-13	2026-08-14	75,834	$117.38	$8.90M	0	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2026-08-13	2026-08-17	3,400	$118.28	$402.2K	3,095	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2026-08-13	2026-08-17	2,007	$116.11	$233.0K	8,051	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2026-08-13	2026-08-17	800	$119.17	$95.3K	2,295	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2026-08-13	2026-08-17	1,556	$117.08	$182.2K	6,495	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2026-08-13	2026-08-17	2,024	$6.80	$13.8K	20,994	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2026-08-13	2026-08-17	5,079	$119.75	$608.2K	15,915	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise deriv	2026-08-13	2026-08-14	21,601	—	$0	0	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise deriv	2026-08-13	2026-08-14	35,000	—	$0	36,283	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	S Sale	2026-08-13	2026-08-14	75,834	$117.38	$8.90M	0	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise	2026-08-13	2026-08-14	21,601	$6.80	$146.9K	75,834	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise	2026-08-13	2026-08-14	35,000	$24.29	$850.1K	54,233	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2026-08-13	2026-08-17	2,024	—	$0	5,945	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2026-08-13	2026-08-17	5,079	$119.75	$608.2K	15,915	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2026-08-13	2026-08-17	2,024	$6.80	$13.8K	20,994	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2026-08-13	2026-08-17	800	$119.17	$95.3K	2,295	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2026-08-13	2026-08-17	3,400	$118.28	$402.2K	3,095	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2026-08-13	2026-08-17	1,556	$117.08	$182.2K	6,495	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2026-08-13	2026-08-17	2,007	$116.11	$233.0K	8,051	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise deriv	2026-08-12	2026-08-14	46,625	—	$0	35,875	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	3,605	$114.70	$413.5K	105,750	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise	2026-08-12	2026-08-14	46,625	$6.80	$317.1K	112,655	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	2,300	$111.80	$257.1K	110,355	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	1,000	$112.86	$112.9K	109,355	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	17,319	$117.47	$2.03M	55,655	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	18,208	$116.49	$2.12M	72,974	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	14,568	$115.43	$1.68M	91,182	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise deriv	2026-08-12	2026-08-14	46,625	—	$0	35,875	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	17,319	$117.47	$2.03M	55,655	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	18,208	$116.49	$2.12M	72,974	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	14,568	$115.43	$1.68M	91,182	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	3,605	$114.70	$413.5K	105,750	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	1,000	$112.86	$112.9K	109,355	SEC↗
Mazabraud Yann	EVP, Head of International	S Sale	2026-08-12	2026-08-14	2,300	$111.80	$257.1K	110,355	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise	2026-08-12	2026-08-14	46,625	$6.80	$317.1K	112,655	SEC↗
Garfield Alastair	Chief Scientific Officer	M Exercise deriv	2026-07-01	2026-07-02	4,445	—	$0	8,888	SEC↗
Garfield Alastair	Chief Scientific Officer	F Tax w/h	2026-07-01	2026-07-02	2,150	$110.41	$237.4K	10,058	SEC↗
Garfield Alastair	Chief Scientific Officer	M Exercise	2026-07-01	2026-07-02	4,445	—	$0	12,208	SEC↗
GOOD JENNIFER L	Director	A Award deriv	2026-06-24	2026-06-25	3,691	—	$0	3,691	SEC↗
GOOD JENNIFER L	Director	A Award deriv	2026-06-24	2026-06-25	2,324	—	$0	2,324	SEC↗
Arbuckle Stuart A	Director	A Award deriv	2026-06-24	2026-06-25	3,691	—	$0	3,691	SEC↗
Arbuckle Stuart A	Director	A Award deriv	2026-06-24	2026-06-25	2,324	—	$0	2,324	SEC↗
TETRAULT LYNN A.	Director	A Award deriv	2026-06-24	2026-06-25	3,691	—	$0	3,691	SEC↗
TETRAULT LYNN A.	Director	A Award deriv	2026-06-24	2026-06-25	2,324	—	$0	2,324	SEC↗
MCGIRR DAVID W J	Director	A Award deriv	2026-06-24	2026-06-25	3,691	—	$0	3,691	SEC↗
MCGIRR DAVID W J	Director	A Award deriv	2026-06-24	2026-06-25	2,324	—	$0	2,324	SEC↗
JEAN CHRISTOPHE	Director	A Award deriv	2026-06-24	2026-06-25	3,691	—	$0	3,691	SEC↗
JEAN CHRISTOPHE	Director	A Award deriv	2026-06-24	2026-06-25	2,324	—	$0	2,324	SEC↗
GOOD JENNIFER L	Director	M Exercise deriv	2026-06-23	2026-06-25	4,712	—	$0	0	SEC↗
Arbuckle Stuart A	Director	M Exercise deriv	2026-06-23	2026-06-25	4,712	—	$0	0	SEC↗
TETRAULT LYNN A.	Director	M Exercise deriv	2026-06-23	2026-06-25	4,712	—	$0	0	SEC↗
MCGIRR DAVID W J	Director	M Exercise deriv	2026-06-23	2026-06-25	4,712	—	$0	0	SEC↗
JEAN CHRISTOPHE	Director	M Exercise deriv	2026-06-23	2026-06-25	4,712	—	$0	0	SEC↗
GOOD JENNIFER L	Director	M Exercise	2026-06-23	2026-06-25	4,712	—	$0	11,712	SEC↗
Arbuckle Stuart A	Director	M Exercise	2026-06-23	2026-06-25	4,712	—	$0	11,712	SEC↗
TETRAULT LYNN A.	Director	M Exercise	2026-06-23	2026-06-25	4,712	—	$0	11,712	SEC↗
MCGIRR DAVID W J	Director	M Exercise	2026-06-23	2026-06-25	4,712	—	$0	11,712	SEC↗
JEAN CHRISTOPHE	Director	M Exercise	2026-06-23	2026-06-25	4,712	—	$0	11,712	SEC↗
TETRAULT LYNN A.	Director	M Exercise deriv	2026-06-22	2026-06-24	37,000	—	$0	0	SEC↗
TETRAULT LYNN A.	Director	M Exercise	2026-06-22	2026-06-24	37,000	$28.27	$1.05M	44,000	SEC↗
TETRAULT LYNN A.	Director	S Sale	2026-06-22	2026-06-24	37,000	$100.32	$3.71M	7,000	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2026-05-18	2026-05-20	3,000	—	$0	79,000	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2026-05-18	2026-05-20	3,000	$17.87	$53.6K	119,611	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2026-05-15	2026-05-19	1,349	—	$0	2,701	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2026-05-15	2026-05-19	1,687	—	$0	3,713	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2026-05-15	2026-05-19	1,406	—	$0	2,325	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2026-05-15	2026-05-19	1,687	$56.69	$95.6K	1,888	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2026-05-15	2026-05-19	1,349	$49.23	$66.4K	3,237	SEC↗
German Christopher Paul	Corporate Controller & CAO	S Sale	2026-05-15	2026-05-19	4,643	$92.21	$428.1K	0	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2026-05-15	2026-05-19	1,406	$17.97	$25.3K	4,643	SEC↗
Popovits Kimberly J	Director	A Award deriv	2026-04-01	2026-04-03	6,808	—	$0	6,808	SEC↗
Popovits Kimberly J	Director	A Award deriv	2026-04-01	2026-04-03	10,257	—	$0	10,257	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise deriv	2026-04-01	2026-04-03	10,375	—	$0	10,375	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise deriv	2026-04-01	2026-04-03	2,500	—	$0	5,000	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise	2026-04-01	2026-04-03	12,875	—	$0	66,030	SEC↗
Mathers Edward T	Director	J Other	2026-03-12	2026-03-16	4,199	—	$0	14,168	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2026-03-04	2026-03-06	1,500	—	$0	3,731	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2026-03-04	2026-03-06	1,500	$17.97	$27.0K	5,753	SEC↗
German Christopher Paul	Corporate Controller & CAO	S Sale	2026-03-04	2026-03-06	5,614	$89.56	$502.8K	160	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2026-03-02	2026-03-02	6,099	—	$0	91,401	SEC↗
Mazabraud Yann	EVP, Head of International	A Award deriv	2026-03-02	2026-03-04	35,000	—	$0	35,000	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2026-03-02	2026-03-02	6,099	$6.80	$41.5K	116,611	SEC↗
Mathers Edward T	Director	J Other	2026-03-02	2026-03-04	4,198	—	$0	9,969	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2026-03-01	2026-03-03	1,162	—	$0	1,162	SEC↗
German Christopher Paul	Corporate Controller & CAO	F Tax w/h	2026-03-01	2026-03-03	342	$94.94	$32.5K	4,253	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2026-03-01	2026-03-03	1,162	—	$0	4,595	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-19	2026-02-19	585	$103.28	$60.4K	110,512	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-19	2026-02-19	800	$102.10	$81.7K	111,097	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-19	2026-02-19	1,692	$100.92	$170.8K	111,897	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-19	2026-02-19	1,308	$100.27	$131.2K	113,589	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-17	2026-02-19	200	$103.84	$20.8K	114,897	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-17	2026-02-19	1,200	$99.42	$119.3K	117,266	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-17	2026-02-19	1,069	$103.00	$110.1K	115,097	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-17	2026-02-19	900	$101.70	$91.5K	116,166	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-17	2026-02-19	200	$100.52	$20.1K	117,066	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise deriv	2026-02-14	2026-02-18	10,000	—	$0	30,000	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise	2026-02-14	2026-02-18	10,000	—	$0	53,155	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-12	2026-02-12	292	$96.26	$28.1K	119,766	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-12	2026-02-12	400	$97.67	$39.1K	119,366	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-12	2026-02-12	800	$98.99	$79.2K	118,566	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-12	2026-02-12	100	$100.10	$10.0K	118,466	SEC↗
Smith Hunter C	Chief Financial Officer	A Award deriv	2026-02-11	2026-02-12	37,500	—	$0	37,500	SEC↗
Smith Hunter C	Chief Financial Officer	A Award deriv	2026-02-11	2026-02-12	25,000	—	$0	25,000	SEC↗
Cramer Pamela J.	Chief Human Resources Office	A Award deriv	2026-02-11	2026-02-13	17,500	—	$0	17,500	SEC↗
Cramer Pamela J.	Chief Human Resources Office	A Award deriv	2026-02-11	2026-02-13	11,650	—	$0	11,650	SEC↗
Garfield Alastair	Chief Scientific Officer	A Award deriv	2026-02-11	2026-02-13	16,650	—	$0	16,650	SEC↗
Garfield Alastair	Chief Scientific Officer	A Award deriv	2026-02-11	2026-02-13	25,000	—	$0	25,000	SEC↗
German Christopher Paul	Corporate Controller & CAO	A Award deriv	2026-02-11	2026-02-13	5,215	—	$0	5,215	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	A Award deriv	2026-02-11	2026-02-13	21,650	—	$0	21,650	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	A Award deriv	2026-02-11	2026-02-13	32,500	—	$0	32,500	SEC↗
Mazabraud Yann	EVP, Head of International	A Award deriv	2026-02-11	2026-02-13	23,350	—	$0	23,350	SEC↗
Meeker David P	President and CEO	A Award deriv	2026-02-11	2026-02-13	107,850	—	$0	107,850	SEC↗
Meeker David P	President and CEO	A Award deriv	2026-02-11	2026-02-13	71,900	—	$0	71,900	SEC↗
Shulman Joseph	Chief Technical Officer	A Award deriv	2026-02-11	2026-02-13	15,000	—	$0	15,000	SEC↗
Shulman Joseph	Chief Technical Officer	A Award deriv	2026-02-11	2026-02-13	22,500	—	$0	22,500	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-11	2026-02-12	400	$99.44	$39.8K	120,158	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-11	2026-02-12	100	$100.85	$10.1K	120,058	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-11	2026-02-12	2,266	$98.37	$222.9K	120,558	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-10	2026-02-12	1,913	$102.66	$196.4K	123,624	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-10	2026-02-12	100	$104.76	$10.5K	122,824	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-10	2026-02-12	700	$103.68	$72.6K	122,924	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-05	2026-02-06	3,381	$106.06	$358.6K	125,537	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-04	2026-02-06	1,000	$106.60	$106.6K	129,665	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-04	2026-02-06	747	$107.67	$80.4K	128,918	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2026-02-04	2026-02-06	1,500	$104.74	$157.1K	130,665	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2026-02-01	2026-02-03	5,000	—	$0	15,000	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2026-02-01	2026-02-03	2,343	—	$0	0	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2026-02-01	2026-02-03	3,300	—	$0	6,600	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2026-02-01	2026-02-03	2,650	—	$0	2,650	SEC↗
Garfield Alastair	Chief Scientific Officer	M Exercise deriv	2026-02-01	2026-02-03	6,663	—	$0	19,987	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2026-02-01	2026-02-03	1,807	—	$0	5,418	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2026-02-01	2026-02-03	1,806	—	$0	3,612	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise deriv	2026-02-01	2026-02-03	9,163	—	$0	27,487	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise deriv	2026-02-01	2026-02-03	3,437	—	$0	0	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise deriv	2026-02-01	2026-02-03	4,512	—	$0	4,512	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise deriv	2026-02-01	2026-02-03	5,500	—	$0	11,000	SEC↗
Meeker David P	President and CEO	M Exercise deriv	2026-02-01	2026-02-03	14,125	—	$0	14,125	SEC↗
Meeker David P	President and CEO	M Exercise deriv	2026-02-01	2026-02-03	33,338	—	$0	100,012	SEC↗
Meeker David P	President and CEO	M Exercise deriv	2026-02-01	2026-02-03	21,250	—	$0	42,500	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2026-02-01	2026-02-03	2,656	—	$0	0	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2026-02-01	2026-02-03	3,937	—	$0	3,937	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2026-02-01	2026-02-03	4,125	—	$0	8,250	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2026-02-01	2026-02-03	6,250	—	$0	18,750	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2026-02-01	2026-02-03	10,413	—	$0	31,237	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2026-02-01	2026-02-03	4,062	—	$0	0	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2026-02-01	2026-02-03	4,925	—	$0	4,925	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2026-02-01	2026-02-03	6,600	—	$0	13,200	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise deriv	2026-02-01	2026-02-03	5,500	—	$0	11,000	SEC↗
Cramer Pamela J.	Chief Human Resources Office	F Tax w/h	2026-02-01	2026-02-03	4,731	$108.99	$515.6K	29,376	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2026-02-01	2026-02-03	13,293	—	$0	34,107	SEC↗
Garfield Alastair	Chief Scientific Officer	F Tax w/h	2026-02-01	2026-02-03	2,026	$108.99	$220.8K	7,763	SEC↗
Garfield Alastair	Chief Scientific Officer	M Exercise	2026-02-01	2026-02-03	6,663	—	$0	9,789	SEC↗
German Christopher Paul	Corporate Controller & CAO	F Tax w/h	2026-02-01	2026-02-03	1,138	$108.99	$124.0K	3,433	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2026-02-01	2026-02-03	3,613	—	$0	4,571	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	M Exercise	2026-02-01	2026-02-03	22,612	—	$0	28,470	SEC↗
Lee Jennifer Kayden	EVP, Head of North America	F Tax w/h	2026-02-01	2026-02-03	9,237	$108.99	$1.01M	19,233	SEC↗
Meeker David P	President and CEO	M Exercise	2026-02-01	2026-02-03	68,713	—	$0	270,538	SEC↗
Meeker David P	President and CEO	F Tax w/h	2026-02-01	2026-02-03	31,522	$108.99	$3.44M	239,016	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2026-02-01	2026-02-03	16,968	—	$0	25,477	SEC↗
Shulman Joseph	Chief Technical Officer	F Tax w/h	2026-02-01	2026-02-03	6,507	$108.99	$709.2K	18,970	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2026-02-01	2026-02-03	26,000	—	$0	142,915	SEC↗
Smith Hunter C	Chief Financial Officer	F Tax w/h	2026-02-01	2026-02-03	10,750	$108.99	$1.17M	132,165	SEC↗
Mazabraud Yann	EVP, Head of International	M Exercise	2026-02-01	2026-02-03	5,500	—	$0	43,155	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2025-12-11	2025-12-15	3,350	—	$0	8,375	SEC↗
Cramer Pamela J.	Chief Human Resources Office	S Sale	2025-12-11	2025-12-15	3,350	$111.00	$371.9K	20,814	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2025-12-11	2025-12-15	3,350	$27.35	$91.6K	24,164	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2025-11-20	2025-11-24	3,350	—	$0	11,725	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2025-11-20	2025-11-24	3,350	$27.35	$91.6K	24,164	SEC↗
Cramer Pamela J.	Chief Human Resources Office	S Sale	2025-11-20	2025-11-24	3,350	$105.00	$351.8K	20,814	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2025-11-10	2025-11-12	3,515	—	$0	3,520	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2025-11-10	2025-11-12	3,515	$6.80	$23.9K	24,329	SEC↗
Cramer Pamela J.	Chief Human Resources Office	S Sale	2025-11-10	2025-11-12	3,515	$100.00	$351.5K	20,814	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2025-11-07	2025-11-12	10,546	—	$0	7,035	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2025-11-07	2025-11-12	8,805	—	$0	5,257	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2025-11-07	2025-11-12	8,805	$19.02	$167.5K	29,619	SEC↗
Cramer Pamela J.	Chief Human Resources Office	S Sale	2025-11-07	2025-11-12	19,351	$98.82	$1.91M	20,814	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2025-11-07	2025-11-12	10,546	$6.80	$71.7K	40,165	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-10-30	2025-11-03	9,748	—	$0	0	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-10-30	2025-11-03	9,748	$115.24	$1.12M	8,509	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-10-30	2025-11-03	9,748	$30.66	$298.9K	18,257	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-10-28	2025-10-30	2,094	—	$0	12,563	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-10-28	2025-10-30	721	—	$0	9,748	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-10-28	2025-10-30	2,815	$115.01	$323.8K	8,509	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-10-28	2025-10-30	721	$30.66	$22.1K	11,324	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-10-28	2025-10-30	2,094	$27.35	$57.3K	10,603	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-10-16	2025-10-20	12,344	—	$0	10,469	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-10-16	2025-10-20	2,093	—	$0	14,657	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-10-16	2025-10-20	2,693	$110.95	$298.8K	20,253	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-10-16	2025-10-20	2,093	$27.35	$57.2K	10,602	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-10-16	2025-10-20	8,332	$112.06	$933.7K	11,921	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-10-16	2025-10-20	3,412	$112.81	$384.9K	8,509	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-10-16	2025-10-20	12,344	$30.66	$378.5K	22,946	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-09-02	2025-09-04	14,687	—	$0	22,813	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-09-02	2025-09-04	2,094	—	$0	16,750	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-09-02	2025-09-04	2,094	$27.35	$57.3K	10,603	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-09-02	2025-09-04	16,781	$105.30	$1.77M	8,509	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-09-02	2025-09-04	14,687	$30.66	$450.3K	25,290	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-08-21	2025-08-25	4,188	—	$0	18,844	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-08-21	2025-08-25	4,188	$27.35	$114.5K	12,697	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-08-21	2025-08-25	4,188	$100.07	$419.1K	8,509	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2025-08-13	2025-08-14	3,477	—	$0	0	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2025-08-13	2025-08-14	3,477	$6.88	$23.9K	120,392	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2025-08-13	2025-08-14	3,477	$96.00	$333.8K	116,915	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2025-08-12	2025-08-14	1,000	—	$0	5,231	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2025-08-12	2025-08-14	500	—	$0	4,050	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2025-08-12	2025-08-14	24,611	—	$0	3,477	SEC↗
German Christopher Paul	Corporate Controller & CAO	S Sale	2025-08-12	2025-08-14	1,500	$95.00	$142.5K	922	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2025-08-12	2025-08-14	500	$49.23	$24.6K	1,422	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2025-08-12	2025-08-14	1,000	$17.97	$18.0K	1,922	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2025-08-12	2025-08-14	24,611	$6.88	$169.3K	141,526	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2025-08-12	2025-08-14	24,611	$96.33	$2.37M	116,915	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-08-11	2025-08-13	3,984	—	$0	7,969	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-08-11	2025-08-13	3,984	$6.80	$27.1K	12,493	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-08-11	2025-08-13	3,984	$90.08	$358.9K	8,509	SEC↗
Cramer Pamela J.	Chief Human Resources Office	S Sale	2025-07-29	2025-07-29	1,520	$85.93	$130.6K	20,814	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2025-07-26	2025-07-29	3,125	—	$0	0	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2025-07-26	2025-07-29	3,125	—	$0	22,334	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2025-07-09	2025-07-11	10,547	—	$0	17,581	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise deriv	2025-07-09	2025-07-11	5,025	—	$0	15,075	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2025-07-09	2025-07-11	850	—	$0	4,550	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise deriv	2025-07-09	2025-07-11	2,000	—	$0	6,231	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise deriv	2025-07-09	2025-07-11	7,969	—	$0	11,953	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2025-07-09	2025-07-11	42,120	—	$0	28,088	SEC↗
Cramer Pamela J.	Chief Human Resources Office	S Sale	2025-07-09	2025-07-11	7,831	$76.69	$600.6K	22,725	SEC↗
Cramer Pamela J.	Chief Human Resources Office	S Sale	2025-07-09	2025-07-11	3,516	$80.00	$281.3K	19,209	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2025-07-09	2025-07-11	5,025	$27.35	$137.4K	34,781	SEC↗
Cramer Pamela J.	Chief Human Resources Office	M Exercise	2025-07-09	2025-07-11	10,547	$6.80	$71.7K	29,756	SEC↗
Cramer Pamela J.	Chief Human Resources Office	S Sale	2025-07-09	2025-07-11	4,225	$75.55	$319.2K	30,556	SEC↗
German Christopher Paul	Corporate Controller & CAO	S Sale	2025-07-09	2025-07-11	1,967	$76.75	$151.0K	2,772	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2025-07-09	2025-07-11	850	$49.23	$41.8K	4,739	SEC↗
German Christopher Paul	Corporate Controller & CAO	M Exercise	2025-07-09	2025-07-11	2,000	$17.97	$35.9K	3,889	SEC↗
German Christopher Paul	Corporate Controller & CAO	S Sale	2025-07-09	2025-07-11	1,850	$85.00	$157.3K	922	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-07-09	2025-07-11	3,985	$80.00	$318.8K	8,509	SEC↗
Shulman Joseph	Chief Technical Officer	S Sale	2025-07-09	2025-07-11	3,984	$75.56	$301.0K	12,494	SEC↗
Shulman Joseph	Chief Technical Officer	M Exercise	2025-07-09	2025-07-11	7,969	$6.80	$54.2K	16,478	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2025-07-09	2025-07-11	1,607	$76.17	$122.4K	140,315	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2025-07-09	2025-07-11	42,120	$6.88	$289.8K	159,035	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2025-07-09	2025-07-11	17,113	$75.38	$1.29M	141,922	SEC↗
Smith Hunter C	Chief Financial Officer	S Sale	2025-07-09	2025-07-11	23,400	$84.50	$1.98M	116,915	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise deriv	2025-07-07	2025-07-08	6,986	—	$0	70,208	SEC↗
Smith Hunter C	Chief Financial Officer	M Exercise	2025-07-07	2025-07-08	6,986	$6.88	$48.1K	116,915	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2025-07-02	2025-07-03	6	$64.60	$388	3,126	SEC↗
Garfield Alastair	Chief Scientific Officer	S Sale	2025-07-02	2025-07-03	1,313	$64.81	$85.1K	3,132	SEC↗
Garfield Alastair	Chief Scientific Officer	M Exercise deriv	2025-07-01	2025-07-03	4,445	—	$0	13,333	SEC↗
Garfield Alastair	Chief Scientific Officer	M Exercise	2025-07-01	2025-07-03	4,445	—	$0	4,445	SEC↗
MCGIRR DAVID W J	Director	A Award deriv	2025-06-24	2025-06-26	4,712	—	$0	4,712	SEC↗
MCGIRR DAVID W J	Director	A Award deriv	2025-06-24	2025-06-26	7,037	—	$0	7,037	SEC↗
TETRAULT LYNN A.	Director	A Award deriv	2025-06-24	2025-06-26	7,037	—	$0	7,037	SEC↗
TETRAULT LYNN A.	Director	A Award deriv	2025-06-24	2025-06-26	4,712	—	$0	4,712	SEC↗
Arbuckle Stuart A	Director	A Award deriv	2025-06-24	2025-06-26	4,712	—	$0	4,712	SEC↗
Arbuckle Stuart A	Director	A Award deriv	2025-06-24	2025-06-26	7,037	—	$0	7,037	SEC↗
JEAN CHRISTOPHE	Director	A Award deriv	2025-06-24	2025-06-26	7,037	—	$0	7,037	SEC↗
JEAN CHRISTOPHE	Director	A Award deriv	2025-06-24	2025-06-26	4,712	—	$0	4,712	SEC↗
Mathers Edward T	Director	A Award deriv	2025-06-24	2025-06-26	4,712	—	$0	4,712	SEC↗
Mathers Edward T	Director	A Award deriv	2025-06-24	2025-06-26	7,037	—	$0	7,037	SEC↗
GOOD JENNIFER L	Director	A Award deriv	2025-06-24	2025-06-26	4,712	—	$0	4,712	SEC↗
GOOD JENNIFER L	Director	A Award deriv	2025-06-24	2025-06-26	7,037	—	$0	7,037	SEC↗
Bedrosian Camille L	Director	A Award deriv	2025-06-24	2025-06-26	4,712	—	$0	4,712	SEC↗
Bedrosian Camille L	Director	A Award deriv	2025-06-24	2025-06-26	7,037	—	$0	7,037	SEC↗
TETRAULT LYNN A.	Director	M Exercise deriv	2025-06-18	2025-06-23	4,000	—	$0	0	SEC↗
MCGIRR DAVID W J	Director	M Exercise deriv	2025-06-18	2025-06-23	4,000	—	$0	0	SEC↗
Arbuckle Stuart A	Director	M Exercise deriv	2025-06-18	2025-06-23	4,000	—	$0	0	SEC↗
Bedrosian Camille L	Director	M Exercise deriv	2025-06-18	2025-06-23	4,000	—	$0	0	SEC↗
GOOD JENNIFER L	Director	M Exercise deriv	2025-06-18	2025-06-23	4,000	—	$0	0	SEC↗
JEAN CHRISTOPHE	Director	M Exercise deriv	2025-06-18	2025-06-23	4,000	—	$0	0	SEC↗
Mathers Edward T	Director	M Exercise deriv	2025-06-18	2025-06-23	4,000	—	$0	0	SEC↗
TETRAULT LYNN A.	Director	M Exercise	2025-06-18	2025-06-23	4,000	—	$0	7,000	SEC↗